Lysosomal hydrolase dysfunction and autophagic flux impairment in ischemic stroke: Molecular mechanisms, cellular consequences, and therapeutic perspectives
September 2026
Ischemic stroke carries high rates of incidence, disability, mortality, and recurrence, representing a major global health challenge with substantial socioeconomic and healthcare impacts. Interruption...
Establishment and evaluation of animal models of sleep disorders
September 2026
Sleep disorders are common neuropsychiatric diseases that seriously affect human physical and mental health. Their occurrence and progression involve multiple complex mechanisms, including neurotransmitter...
Neural circuit remodeling after spinal cord injury: Mechanisms and translational perspectives
September 2026
Spinal cord injury (SCI) is widely recognized as a devastating neurological condition that causes severe impairment of motor, sensory, and autonomic functions. Due to its complex pathophysiology, curative...
Role of PYHIN1 inhibition in neuroprotection against Aβ-induced hippocampal neuronal injury
September 2026
To explore the role of PYHIN1 in Alzheimer disease (AD) and provide potential targets and experimental evidence for its diagnosis and treatment....